KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
39.7
Human Site:
Y197
Identified Species:
62.38
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
Y197
Q
E
L
D
F
R
H
Y
S
I
K
V
V
P
V
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
Y197
Q
E
L
D
F
R
H
Y
S
I
K
V
V
P
V
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
Y197
Q
E
L
D
F
R
H
Y
S
I
K
V
V
P
V
Dog
Lupus familis
XP_533920
792
88144
Y197
Q
E
L
D
F
R
H
Y
S
I
K
V
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
Y197
Q
E
L
D
F
R
H
Y
S
V
K
V
V
P
V
Rat
Rattus norvegicus
NP_001011980
470
52521
Y197
Q
E
L
D
F
R
H
Y
S
I
K
V
V
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
Y197
Q
L
L
D
F
R
H
Y
S
L
K
V
V
P
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
Y196
Q
E
V
E
F
R
H
Y
S
L
K
V
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
Y196
K
L
V
E
M
R
H
Y
S
V
Q
V
V
P
V
Honey Bee
Apis mellifera
XP_395421
413
48031
S190
M
Q
L
K
L
I
A
S
M
F
Q
N
M
F
P
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
F225
D
E
I
Q
M
R
H
F
A
I
R
V
V
A
S
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
V80
G
V
A
G
P
L
G
V
S
H
F
L
S
Y
T
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
S77
V
A
G
P
M
G
V
S
H
F
L
I
L
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
D125
H
Q
Y
S
L
A
S
D
I
A
Q
S
Q
L
R
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
Y206
G
E
I
S
M
R
H
Y
F
I
D
I
R
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
N.A.
80
N.A.
53.3
6.6
40
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
100
N.A.
86.6
26.6
66.6
13.3
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
0
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
7
0
7
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
47
0
0
0
7
0
0
7
0
0
0
0
% D
% Glu:
0
60
0
14
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
54
0
0
7
7
14
7
0
0
7
0
% F
% Gly:
14
0
7
7
0
7
7
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
74
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
7
0
0
7
47
0
14
0
0
0
% I
% Lys:
7
0
0
7
0
0
0
0
0
0
54
0
0
0
7
% K
% Leu:
0
14
54
0
14
7
0
0
0
14
7
7
7
7
0
% L
% Met:
7
0
0
0
27
0
0
0
7
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
0
0
0
60
7
% P
% Gln:
54
14
0
7
0
0
0
0
0
0
20
0
7
0
0
% Q
% Arg:
0
0
0
0
0
74
0
0
0
0
7
0
7
0
7
% R
% Ser:
0
0
0
14
0
0
7
14
67
0
0
7
7
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
7
7
14
0
0
0
7
7
0
14
0
67
67
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
67
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _